A mutated beta-catenin gene encodes a melanoma-specific antigen recognized by tumor infiltrating lymphocytes

@article{Robbins1996AMB,
  title={A mutated beta-catenin gene encodes a melanoma-specific antigen recognized by tumor infiltrating lymphocytes},
  author={Paul F. Robbins and Mona El-Gamil and Yong Fuga Li and Yutaka Kawakami and Douglas J. Loftus and Ettore Appella and Steven A Rosenberg},
  journal={The Journal of Experimental Medicine},
  year={1996},
  volume={183},
  pages={1185 - 1192}
}
A number of antigens recognized by tumor-reactive T cells have recently been identified. The antigens identified in mouse model systems appear, with one exception, to represent the products of mutated genes. In contrast, most of the antigens recognized by human tumor-reactive T cells reported to date appear to represent the products of non-mutated genes. Here we report the isolation of a cDNA clone encoding beta-catenin, which was shown to be recognized by the tumor-infiltrating lymphocyte (TIL… CONTINUE READING

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References

Publications referenced by this paper.
SHOWING 1-10 OF 31 REFERENCES

Prominent roles of secondary anchor residues in peptide binding to HLAA'2401 human class I molecules..], lmmunot

A. Kondo, J. Sidney, +4 authors E. Celis
  • 1995
VIEW 4 EXCERPTS
HIGHLY INFLUENTIAL

A mutated intron sequence codes for an antigenic peptide recognized by cytolytic T lymphocytes on a human melanoma.

  • Proceedings of the National Academy of Sciences of the United States of America
  • 1995
VIEW 2 EXCERPTS

A new family of genes coding for an antigen recognized by autologous cytolytic T lymphocytes on a human melanoma

E. DePlaen, B. Lethe, P. Coulie, T. Boon
  • J . Exp . Med .
  • 1995

A new family of genes coding for an antigen recognized by autologous cytolytic T lymphocytes on a human melanoma.J

B. Van Den Eynde, O. Peeters, +3 authors T. Boon
  • Exp. Med
  • 1995
VIEW 2 EXCERPTS

Cloning of a new gene encoding an antigen recognized by melanoma-specific HLA-A24 restricted tumor-infiltrating lymphocytes

P. F. Robbins, M. E1-Gamil, +6 authors S. A. Rosenberg
  • J. Immunol
  • 1995
VIEW 2 EXCERPTS