A muscular path to quiescence

  title={A muscular path to quiescence},
  author={William A. Wells},
  journal={The Journal of Cell Biology},
  pages={304 - 304}
A muscular path to quiescence uscle stem cells called satellite cells can pull back from the brink, according to Zammit et al. (page 347). When activated by muscle damage, the cells divide and start uniformly down a differentiation path. Only at the last minute do some of the cells split off to revert to a quiescent, stem cell phenotype. Satellite cells sit quietly underneath the basal lamina of myofibers until a muscle is damaged. Either mitogens leaking into a damaged muscle or signals from a… CONTINUE READING