A murine model of coxsackievirus A16 infection for anti-viral evaluation.

@article{Liu2014AMM,
  title={A murine model of coxsackievirus A16 infection for anti-viral evaluation.},
  author={Qingwei Liu and Jinping Shi and Xulin Huang and Fei Liu and Yicun Cai and Ke Lan and Zhong Huang},
  journal={Antiviral research},
  year={2014},
  volume={105},
  pages={
          26-31
        }
}
Coxsackievirus A16 (CA16) is one of the main causative agents of hand, foot and mouth disease (HFMD), which is a common infectious disease in children. CA16 infection may lead to severe nervous system damage and even death in humans. However, study of the pathogenesis of CA16 infection and development of vaccines and anti-viral agents are hindered partly by the lack of an appropriate small animal model. In the present study, we developed and characterized a murine model of CA16 infection. We… CONTINUE READING

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