A murine T lymphocyte antigen belongs to a supergene family of type II integral membrane proteins.

@article{Yokoyama1989AMT,
  title={A murine T lymphocyte antigen belongs to a supergene family of type II integral membrane proteins.},
  author={Wayne M Yokoyama and Lori Jacobs and Osami Kanagawa and Ethan M Shevach and David I. Cohen},
  journal={Journal of immunology},
  year={1989},
  volume={143 4},
  pages={1379-86}
}
A murine cell surface, disulfide-linked 85kDa dimer, defined with murine mAb A1, is expressed at high levels on EL-4 cells, but at low levels on normal C57BL/6 T cells. A similar structure is recognized by the rat mAbs YE1/32 and YE1/48. We isolated a cDNA clone encoding the antigen recognized by mAb A1 by immunoselection of a cDNA library in the eukaryotic expression vector CDM8. COS 7.2 cells transfected with this cDNA clone expressed an mAb A1-reactive 85 kDa disulfide-linked dimer with 44… CONTINUE READING
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