A multistep general theory of transition to addiction

@inproceedings{Piazza2013AMG,
  title={A multistep general theory of transition to addiction},
  author={Pier Vincenzo Vincenzo Piazza and V{\'e}ronique Deroche-Gamonet},
  booktitle={Psychopharmacology},
  year={2013}
}
Several theories propose alternative explanations for drug addiction. We propose a general theory of transition to addiction that synthesizes knowledge generated in the field of addiction into a unitary explanatory frame. Transition to addiction results from a sequential three-step interaction between: (1) individual vulnerability; (2) degree/amount of drug exposure. The first step, sporadic recreational drug use is a learning process mediated by overactivation of neurobiological substrates of… CONTINUE READING
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