A multiplicity of muscarinic mechanisms: enough signaling pathways to take your breath away.

@article{Nathanson2000AMO,
  title={A multiplicity of muscarinic mechanisms: enough signaling pathways to take your breath away.},
  author={Neil M. Nathanson},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2000},
  volume={97 12},
  pages={6245-7}
}
  • Neil M. Nathanson
  • Published 2000 in
    Proceedings of the National Academy of Sciences…
S ince the classification by Dale of cholinergic responses as muscarinic or nicotinic and the subsequent identification of acetylcholine as the first neurotransmitter mediating the negative chronotropic response of cardiac muscarinic acetylcholine receptors (mAChR), studies on muscarinic receptors have provided a wealth of new insights that have had a wide impact on neurobiology and pharmacology. Muscarinic receptors are present in neurons in the central and peripheral nervous system, cardiac… CONTINUE READING