A multiplex biomarker approach for the diagnosis of transitional cell carcinoma from canine urine.

@article{Bracha2014AMB,
  title={A multiplex biomarker approach for the diagnosis of transitional cell carcinoma from canine urine.},
  author={Shay Bracha and Michael McNamara and Ian Hilgart and Milan Milovancev and Jan Medlock and Cheri P. Goodall and Samanthi I. Wickramasekara and Claudia S. Maier},
  journal={Analytical biochemistry},
  year={2014},
  volume={455},
  pages={41-7}
}
Transitional cell carcinoma (TCC), the most common cancer of the urinary bladder in dogs, is usually diagnosed at an advanced disease stage with limited response to chemotherapy. Commercial screening tests lack specificity and current diagnostic procedures are invasive. A proof of concept pilot project for analyzing the canine urinary proteome as a noninvasive diagnostic tool for TCC identification was conducted. Urine was collected from 12 dogs in three cohorts (healthy, urinary tract… CONTINUE READING
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