A multiobjective memetic algorithm for PPI network alignment

@article{Clark2015AMM,
  title={A multiobjective memetic algorithm for PPI network alignment},
  author={Connor Clark and Jugal K. Kalita},
  journal={Bioinformatics},
  year={2015},
  volume={31 12},
  pages={1988-98}
}
MOTIVATION There recently has been great interest in aligning protein-protein interaction (PPI) networks to identify potentially orthologous proteins between species. It is thought that the topological information contained in these networks will yield better orthology predictions than sequence similarity alone. Recent work has found that existing aligners have difficulty making use of both topological and sequence similarity when aligning, with either one or the other being better matched… CONTINUE READING
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