A multimodal intervention for patients with secondary progressive multiple sclerosis: feasibility and effect on fatigue.

@article{Bisht2014AMI,
  title={A multimodal intervention for patients with secondary progressive multiple sclerosis: feasibility and effect on fatigue.},
  author={Babita Bisht and Warren G. Darling and Ruth E. Grossmann and E. Torage Shivapour and Susan K. Lutgendorf and Linda G. Snetselaar and Michael J. Hall and M. Bridget Zimmerman and Terry L Wahls},
  journal={Journal of alternative and complementary medicine},
  year={2014},
  volume={20 5},
  pages={
          347-55
        }
}
BACKGROUND Multiple sclerosis is an autoimmune disease influenced by environmental factors. OBJECTIVES The feasibility of a multimodal intervention and its effect on perceived fatigue in patients with secondary progressive multiple sclerosis were assessed. DESIGN/SETTING This was a single-arm, open-label intervention study in an outpatient setting. INTERVENTIONS A multimodal intervention including a modified paleolithic diet with supplements, stretching, strengthening exercises with… Expand
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Paper Mentions

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The purpose of this study is to compare the effect of the Swank Diet (low saturated fat) and the Wahls Elimination Diet (modified paleo) on fatigue levels in individuals with… Expand
ConditionsMultiple Sclerosis, Multiple Sclerosis, Relapsing-Remitting
InterventionBehavioral
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The goal of this project is to critically evaluate the effectiveness of using an online program to improve diet and self-care in patients with multiple sclerosis (MS) and clinically… Expand
ConditionsClinically Isolated Syndrome, Multiple Sclerosis
InterventionBehavioral
University of Iowa
November 2021 - December 2023

62 Citations

Citation Type

Citation Type

Multimodal intervention improves fatigue and quality of life in subjects with progressive multiple sclerosis: a pilot study
TLDR
A multimodal intervention including a modified Paleolithic diet, nutritional supplements, stretching, strengthening exercises with electrical stimulation of trunk and lower limb muscles, and stress management on perceived fatigue and quality of life of persons with progressive MS may reduce fatigue and improvequality of life. Expand
Effects of a multimodal intervention on gait and balance of subjects with progressive multiple sclerosis: a prospective longitudinal pilot study
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A multimodal lifestyle intervention may improve walking performance and balance in subjects with progressive MS who have mild-to-moderate gait impairment, whereas subjects with severe gait impairments may not respond to this intervention. Expand
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A modified Paleolithic diet, exercise, EStim, and stress management intervention like this one has the potential to improve the mood and cognitive symptoms that can lead to considerable suffering in people with MS, potentially improving quality of life and function for people with progressive MS. Expand
Randomized control trial evaluation of a modified Paleolithic dietary intervention in the treatment of relapsing-remitting multiple sclerosis: a pilot study
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A Paleolithic diet may be useful in the treatment and management of MS, by reducing perceived fatigue, increasing mental and physical quality of life, increasing exercise capacity, and improving hand and leg function. Expand
Exploring Wellness Interventions in Progressive Multiple Sclerosis: an Evidence-Based Review
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There is level C evidence (possibly effective; one class II study) for the efficacy of aerobic exercise training on cardiorespiratory fitness in patients with progressive MS. Expand
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This study indicates that a healthy nutritional intervention is well accepted by people with multiple sclerosis and may ameliorate their physical and inflammatory status. Expand
Dietary approaches to treat MS-related fatigue: comparing the modified Paleolithic (Wahls Elimination) and low saturated fat (Swank) diets on perceived fatigue in persons with relapsing-remitting multiple sclerosis: study protocol for a randomized controlled trial
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The purpose of this study is to determine the impact of a modified Paleolithic and low saturated fat diet on perceived fatigue, cognitive and motor symptoms, and quality of life in persons with relapsing-remitting multiple sclerosis (RRMS). Expand
Lipid profile is associated with decreased fatigue in individuals with progressive multiple sclerosis following a diet-based intervention: Results from a pilot study
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Lipid profile variables are associated with improvements in fatigue in progressive MS patients on a diet-based multimodal intervention. Expand
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There is evidence to suggest a potential role for vitamin D supplementation, tobacco smoking cessation, routine exercise, a plant-based, anti-inflammatory diet, and maintenance of emotional well-being as adjunct therapies to DMTs. Expand
The Efficacy of Psychological Interventions for Managing Fatigue in People With Multiple Sclerosis: A Systematic Review and Meta-Analysis
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This study found that the use of psychological interventions for MS-related fatigue management reduced fatigue in PwMS. Expand
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