• Corpus ID: 9227939

A multimeric pole-organizing protein critical for chromosome attachment , division and protein localization in Caulobacter

  title={A multimeric pole-organizing protein critical for chromosome attachment , division and protein localization in Caulobacter},
  author={Gitte Ebersbach and Ariane Briegel and Grant J. Jensen and Christine Jacobs-Wagner},
Cell polarization is an integral part of many unrelated bacterial processes. How intrinsic cell polarization is achieved is poorly understood. Here, we provide evidence that Caulobacter crescentus uses a multimeric pole-organizing factor (PopZ) that serves as a hub to concurrently achieve several polarizing functions. During chromosome segregation, polar PopZ captures the ParB•ori complex and thereby anchors sister chromosomes at opposite poles. This step is essential for stabilizing bipolar… 

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  • R. B. JensenL. Shapiro
  • Biology
    Proceedings of the National Academy of Sciences of the United States of America
  • 1999
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