A multilocus candidate approach identifies ACE and HIF1A as susceptibility genes for cellulite

@article{Emanuele2010AMC,
  title={A multilocus candidate approach identifies ACE and HIF1A as susceptibility genes for cellulite},
  author={Enzo Emanuele and Marco Bertona and Diego Geroldi},
  journal={Journal of the European Academy of Dermatology and Venereology},
  year={2010},
  volume={24}
}
Background  Cellulite is a common complex cosmetic problem for many post‐adolescent women characterised by relief alterations of the skin surface, which give the skin an orange‐peel appearance. Although genetic factors have been suggested to play a role in the development of cellulite, the genetic background of this condition remains unclear. We therefore conducted a multi‐locus genetic study examining the potential associations of candidate gene variants in oestrogen receptors, endothelial… 

Cellulite: a cosmetic or systemic issue? Contemporary views on the etiopathogenesis of cellulite

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There is a significant relationship between low plasma adiponectin levels and the risk of cellulite, and this study showed that there was a statistically significant relationship.

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Cellulite’s aetiology: a review

It is concluded that cellulite is a physiological phenomenon or at least, that it has a physiological origin, which is characteristic of women, and multi‐causal, with the coexistence of a number of factors that trigger, perpetuate, or exacerbate it.

Cellulite's aetiology: a review.

It is concluded that cellulite is a physiological phenomenon or at least, that it has a physiological origin, which is characteristic of women, and multi-causal, with the coexistence of a number of factors that trigger, perpetuate, or exacerbate it.

Effect of cosmetic ingredients as anticellulite agents: synergistic action of actives with in vitro and in vivo efficacy.

A potent cocktail of ingredients that when combined together can act in vitro to markedly improve lipolysis mechanisms and by way of stimulating pro-collagen I can also have an effect on the surrounding extracellular matrix.

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