A multigene urine test for the detection and stratification of bladder cancer in patients presenting with hematuria.

@article{OSullivan2012AMU,
  title={A multigene urine test for the detection and stratification of bladder cancer in patients presenting with hematuria.},
  author={P. E. O'Sullivan and Katrina J. Sharples and Mark E. Dalphin and Peter L Davidson and Peter J Gilling and Lisa M. Cambridge and Justin Harvey and Tumi T. Toro and Nardia Giles and Carthika Luxmanan and Cris Felipe Alves and Han-seung Yoon and Victoria A. Hinder and Jonathan G. Masters and Andrew Kennedy-Smith and Tony Beaven and Parry J Guilford},
  journal={The Journal of urology},
  year={2012},
  volume={188 3},
  pages={741-7}
}
PURPOSE We investigated whether the RNA assay uRNA® and its derivative Cxbladder® have greater sensitivity for the detection of bladder cancer than cytology, NMP22™ BladderChek™ and NMP22™ ELISA, and whether they are useful in risk stratification. MATERIALS AND METHODS A total of 485 patients presenting with gross hematuria but without a history of urothelial cancer were recruited prospectively from 11 urology clinics in Australasia. Voided urine samples were obtained before cystoscopy. The… CONTINUE READING

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