A multidisciplinary approach to characterise exposure risk and toxicological effects of PM₁₀ and PM₂.₅ samples in urban environments.

  title={A multidisciplinary approach to characterise exposure risk and toxicological effects of PM₁₀ and PM₂.₅ samples in urban environments.},
  author={Cristina Reche and T Moreno and Fulvio Amato and Mar elo Viana and Barend L. van Drooge and Hsiao-Chi Chuang and Kelly A B{\'e}rub{\'e} and Tim F Jones and Andr{\'e}s Alastuey and Xavier Querol},
  journal={Ecotoxicology and environmental safety},
Urban aerosol samples collected in Barcelona between 2008 and 2009 were toxicologically characterised by means of two complementary methodologies allowing evaluation of their Reactive Oxidative Stress (ROS)-generating capacity: the plasmid scission assay (PSA) and the dichlorodihydrofluorescin assay (DCFH). The PSA determined the PM dose able to damage 50% of a plasmid DNA molecule (TD(50) values), an indication of the ability of the sample to exert potential oxidative stress, most likely by… CONTINUE READING
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