A multicentre phase II randomised trial of weekly docetaxel/gemcitabine followed by erlotinib on progression, vs the reverse sequence, in elderly patients with advanced non small-cell lung cancer selected with a comprehensive geriatric assessment (the GFPC 0504 study)

@inproceedings{Lecaer2011AMP,
  title={A multicentre phase II randomised trial of weekly docetaxel/gemcitabine followed by erlotinib on progression, vs the reverse sequence, in elderly patients with advanced non small-cell lung cancer selected with a comprehensive geriatric assessment (the GFPC 0504 study)},
  author={H Lecaer and Fabrice Barl{\'e}si and Roman Corre and H. Jullian and Suzana Bota and Lionel Falchero and Alain Vergnen{\`e}gre and C{\'e}cile Dujon and Jean Yves Delhoume and Christos Choua{\"i}d},
  booktitle={British Journal of Cancer},
  year={2011}
}
Background:Elderly cancer patients form a heterogeneous population in which therapeutic decision-making is often difficult. The aim of this randomised phase II trial was to evaluate the feasibility and activity of weekly docetaxel/gemcitabine (DG) followed by erlotinib after progression (arm A) vs erlotinib followed by DG after progression (arm B) in fit elderly patients with advanced non small-cell lung cancer (NSCLC).Methods:Elderly chemotherapy-naive patients with stage IIIB/IV NSCLC were… CONTINUE READING

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