A multicenter pilot-randomized controlled trial of the feasibility of an augmented red blood cell transfusion strategy for patients treated with induction chemotherapy for acute leukemia or stem cell transplantation.

@article{Webert2008AMP,
  title={A multicenter pilot-randomized controlled trial of the feasibility of an augmented red blood cell transfusion strategy for patients treated with induction chemotherapy for acute leukemia or stem cell transplantation.},
  author={Kathryn E Webert and Richard J. Cook and Stephen Couban and Julie B Carruthers and Ker-Ai Lee and Morris A. Blajchman and Jeffrey Howard Lipton and Joseph M. Brandwein and Nancy M. Heddle},
  journal={Transfusion},
  year={2008},
  volume={48 1},
  pages={81-91}
}
BACKGROUND Anemia may be an important factor contributing to an increased risk of bleeding, particularly in patients with thrombocytopenia. STUDY DESIGN AND METHODS A multicenter, single-blinded pilot randomized controlled trial (RCT) was performed to evaluate the feasibility of conducting a larger RCT to determine the effect of the hemoglobin (Hb) concentration on bleeding risk. Patients with acute leukemia receiving induction chemotherapy or those undergoing stem cell transplantation were… CONTINUE READING
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