A multicenter observational study of the potential benefits of initiating combination antiretroviral therapy during acute HIV infection.

@article{Hecht2006AMO,
  title={A multicenter observational study of the potential benefits of initiating combination antiretroviral therapy during acute HIV infection.},
  author={Frederick M. Hecht and Lei Wang and Ann C Collier and Susan J. Little and Martin Markowitz and Joseph B. Margolick and Jess Kilby and Eric S Daar and Brian Conway and Sarah E Holte},
  journal={The Journal of infectious diseases},
  year={2006},
  volume={194 6},
  pages={725-33}
}
OBJECTIVE Uncontrolled studies have suggested a benefit, after treatment discontinuation, of initiating highly active antiretroviral therapy (HAART) during primary human immunodeficiency virus (HIV) infection. We assessed whether initiation of HAART within 2 weeks of (acute treatment) or between 2 weeks and 6 months after (early treatment) HIV seroconversion was associated with improvements in the viral load and the CD4+ T cell count after discontinuation of treatment in an observational cohort… CONTINUE READING
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