A multicenter, open-label, randomized comparison of levofloxacin and azithromycin plus ceftriaxone in hospitalized adults with moderate to severe community-acquired pneumonia.

@article{Frank2002AMO,
  title={A multicenter, open-label, randomized comparison of levofloxacin and azithromycin plus ceftriaxone in hospitalized adults with moderate to severe community-acquired pneumonia.},
  author={Elliott Frank and Jing Liu and Gary T. Kinasewitz and Gregory J. Moran and Margaret P Oross and William H. Olson and Veronica Reichl and Susan E. Freitag and Neelam Bahal and Barbara A. Wiesinger and Alan Tennenberg and James B. Kahn},
  journal={Clinical therapeutics},
  year={2002},
  volume={24 8},
  pages={
          1292-308
        }
}
BACKGROUND Changing etiologic patterns and the growing problem of antimicrobial resistance, particularly an increase in macrolide-resistant pneumococcal bacteremia, are causing physicians to adopt new approaches to the treatment of community-acquired pneumonia (CAP). OBJECTIVE The relative efficacy and tolerability of levofloxacin monotherapy and azithromycin and ceftriaxone combination therapy were assessed in hospitalized adults with moderate to severe CAP. METHODS This Phase IV… CONTINUE READING
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Infectious Diseases Society of America. Practice guidelines for the management of community-acquired pneumonia in adults

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