A multicenter, open label, double tympanocentesis study of high dose cefdinir in children with acute otitis media at high risk of persistent or recurrent infection.

@article{Arguedas2006AMO,
  title={A multicenter, open label, double tympanocentesis study of high dose cefdinir in children with acute otitis media at high risk of persistent or recurrent infection.},
  author={Adriano G. Arguedas and Ron Dagan and Eugene Leibovitz and Alejandro Hoberman and Michael E. Pichichero and Mar{\'i}a Soledad Par{\'i}s},
  journal={The Pediatric infectious disease journal},
  year={2006},
  volume={25 3},
  pages={211-8}
}
BACKGROUND Given the relatively high prevalence of recurrent and persistent acute otitis media (AOM) and the prominent etiologic role of Streptococcus pneumoniae, especially penicillin-nonsusceptible strains in children with these conditions, new alternative treatments are desirable. METHODS Children 6 months-4 years of age with AOM considered to be at risk for recurrent or persistent infection received large dosage cefdinir 25 mg/kg oral suspension once daily for 10 days. Children were… CONTINUE READING

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Clinical practice guidelines : diagnosis and management of acute otitis media

  • Casey, ME Pichichero
  • Pediatrics
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