A multi-stage Gaussian transformation algorithm for clinical laboratory data.

@article{Boyd1982AMG,
  title={A multi-stage Gaussian transformation algorithm for clinical laboratory data.},
  author={James Boyd and David A. Lacher},
  journal={Clinical chemistry},
  year={1982},
  volume={28 8},
  pages={1735-41}
}
We have developed a multi-stage computer algorithm to transform non-normally distributed data to a normal distribution. This transformation is of value for calculation of laboratory reference intervals and for normalization of clinical laboratory variates before applying statistical procedures in which underlying data normality is assumed. The algorithm is able to normalize most laboratory data distributions with either negative or positive coefficients of skewness or kurtosis. Stepwise, a… CONTINUE READING

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