A multi-centre evaluation of eleven clinically feasible brain PET/MRI attenuation correction techniques using a large cohort of patients

  title={A multi-centre evaluation of eleven clinically feasible brain PET/MRI attenuation correction techniques using a large cohort of patients},
  author={Claes N\ohr Ladefoged and Ian Law and Udunna Anazodo and Keith St. Lawrence and David Izquierdo-Garcia and Ciprian Catana and Ninon Burgos and M. Jorge Cardoso and S{\'e}bastien Ourselin and Brian F. Hutton and Ines Merida and Nicolas Costes and Alexander Hammers and Didier Benoit and S\oren Holm and Meher R. Juttukonda and Hongyu An and Jorge Cabello and Mathias Lukas and Stephan G. Nekolla and Sibylle Ilse Ziegler and Matthias Fenchell and Bjoern Jakoby and Michael E. Casey and Tammie L. Benzinger and Liselotte H\ojgaard and Adam Espe Hansen and Flemming Littrup Andersen},
AIM To accurately quantify the radioactivity concentration measured by PET, emission data need to be corrected for photon attenuation; however, the MRI signal cannot easily be converted into attenuation values, making attenuation correction (AC) in PET/MRI challenging. In order to further improve the current vendor-implemented MR-AC methods for absolute quantification, a number of prototype methods have been proposed in the literature. These can be categorized into three types: template/atlas… CONTINUE READING
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