A mouse model for vitiligo.

@article{Lerner1986AMM,
  title={A mouse model for vitiligo.},
  author={Aaron Bunsen Lerner and Tetsuo Shiohara and Raymond E. Boissy and Ken Jacobson and Marilyn Lamoreux and Gisela Moellmann},
  journal={The Journal of investigative dermatology},
  year={1986},
  volume={87 3},
  pages={
          299-304
        }
}
  • Aaron Bunsen Lerner, Tetsuo Shiohara, +3 authors Gisela Moellmann
  • Published in
    The Journal of investigative…
    1986
  • Biology, Medicine
  • As the result of a long search for a depigmenting mouse that could serve as a model for the study of vitiligo, we have located a strain that arose from the C57BL/6J. Its provisional genetic designation is C57BL/6J Ler-vit/vit. This vitiligo mouse has congenital dorsal and ventral white spots (piebaldism) as well as progressive replacement of pigmented hairs by white hairs with each spontaneous molt or after plucking. The lack of pigment is due to the absence of melanocytes from the amelanotic… CONTINUE READING

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