A mouse GM-CSF receptor antibody attenuates neutrophilia in mice exposed to cigarette smoke.


We investigated the role of granulocyte-macrophage colony-stimulating factor (GM-CSF) in a subchronic exposure model of cigarette smoke (CS)-induced inflammation using antibodies directed against GM-CSF or the GM-CSF receptor (GM-CSFR) α-chain. CS-induced mononuclear and neutrophilic inflammation following 4 days of CS exposure in BALB/c mice was assessed… (More)
DOI: 10.1183/09031936.00076210


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