A mouse Fas-associated protein with homology to the human Mort1/FADD protein is essential for Fas-induced apoptosis.

Abstract

The Fas cell surface receptor belongs to the tumor necrosis factor receptor family and can initiate apoptosis in a variety of cell types. Using the Fas cytoplasmic domain as bait in a yeast two-hybrid screening, we isolated a mouse cDNA encoding a 205-amino-acid protein. Its predicted protein sequence shows 68% identity and 80% similarity with the sequence… (More)

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@article{Zhang1996AMF, title={A mouse Fas-associated protein with homology to the human Mort1/FADD protein is essential for Fas-induced apoptosis.}, author={J Zhang and Astar Winoto}, journal={Molecular and cellular biology}, year={1996}, volume={16 6}, pages={2756-63} }