A monoclonal antibody inhibiting leucocyte adhesion blocks induction of IL-2 production but not IL-2 receptor expression.

@article{Lindqvist1987AMA,
  title={A monoclonal antibody inhibiting leucocyte adhesion blocks induction of IL-2 production but not IL-2 receptor expression.},
  author={Christer Lindqvist and Manuel Elkin Patarroyo and Patrick G Beatty and Hans Wigzell},
  journal={Immunology},
  year={1987},
  volume={60 4},
  pages={579-84}
}
Monoclonal antibody 60.3 defines the leucocyte antigen CD 18 and recognizes a cell surface glycoprotein with an apparent molecular weight (MW) of 90,000 expressed by most human peripheral blood and bone marrow cells. This antibody can, among other things, block phorbol ester-induced adhesion among human mononuclear leucocytes. We show in this study that… CONTINUE READING