A monoclonal antibody against the type II isotype of beta-tubulin. Preparation of isotypically altered tubulin.

@article{Banerjee1988AMA,
  title={A monoclonal antibody against the type II isotype of beta-tubulin. Preparation of isotypically altered tubulin.},
  author={Asok Banerjee and Mary Carmen Roach and Katherine A Wall and Melvin Lopata and Don W Cleveland and Richard F. Luduena},
  journal={The Journal of biological chemistry},
  year={1988},
  volume={263 6},
  pages={3029-34}
}
Mammalian brain tubulin consists of several isotypes of alpha and beta subunits that separate on polyacrylamide gels into three electrophoretic classes, designated alpha, beta 1, and beta 2. It has not been possible hitherto to resolve the different isotypes in a functional form. To this end, we have now isolated a monoclonal antibody, using as an immunogen… CONTINUE READING