A molecular study on the evolution of a subtype B variant frequently found in Brazil.

@article{Pinto2008AMS,
  title={A molecular study on the evolution of a subtype B variant frequently found in Brazil.},
  author={M{\^o}nica Edelenyi Pinto and Carlos G. Schrago and Antonio Bas{\'i}lio de Miranda and Claudia A. M. Russo},
  journal={Genetics and molecular research : GMR},
  year={2008},
  volume={7 4},
  pages={
          1031-44
        }
}
In spite of the remarkable diversity of HIV-1 env genes, several amino acids are extremely conserved, probably due to functional constraints. One example is the proline found at the second position of the GPGR motif. Several viruses, however, bear substitutions at this site, for instance, GWGR subtype B variant. GWGR viruses are described in Brazil since the beginning of the epidemics, but the extent of their dispersion or the geographical origin of the variant remains unknown. In the present… CONTINUE READING

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