A molecular relay race: sequential first-passage events to the terminal reaction centre in a cascade of diffusion controlled processes

  title={A molecular relay race: sequential first-passage events to the terminal reaction centre in a cascade of diffusion controlled processes},
  author={Denis S. Grebenkov and Ralf Metzler and Gleb Oshanin},
  journal={New Journal of Physics},
We consider a sequential cascade of molecular first-reaction events towards a terminal reaction centre in which each reaction step is controlled by diffusive motion of the particles. The model studied here represents a typical reaction setting encountered in diverse molecular biology systems, in which, e.g. a signal transduction proceeds via a series of consecutive ‘messengers’: the first messenger has to find its respective immobile target site triggering a launch of the second messenger, the… 
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  • Benichou, Moreau, Oshanin
  • Mathematics, Medicine
    Physical review. E, Statistical physics, plasmas, fluids, and related interdisciplinary topics
  • 2000
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