A molecular modelling study on the hormone binding site of the estrogen receptor.

@article{Hltje1993AMM,
  title={A molecular modelling study on the hormone binding site of the estrogen receptor.},
  author={Hans Dieter H{\"o}ltje and N Dall},
  journal={Die Pharmazie},
  year={1993},
  volume={48 4},
  pages={243-9}
}
Using molecular modelling techniques, the structures of ligands with high affinity to the estrogen receptor were investigated. In order to determine the biologically active conformations and orientations within the hormone binding site a comparative study on the basis of molecular shapes and molecular fields was performed. The corresponding pharmacophore… CONTINUE READING