A molecular model of artificial glycoprotein with predetermined multiple immunodeterminants for gram-positive and gram-negative encapsulated bacteria.

@article{Porro1986AMM,
  title={A molecular model of artificial glycoprotein with predetermined multiple immunodeterminants for gram-positive and gram-negative encapsulated bacteria.},
  author={Michele Porro and Paolo Costantino and Francesco Giovannoni and Virginia A Pellegrini and Luca Tagliaferri and F Vannozzi and Stefania Viti},
  journal={Molecular immunology},
  year={1986},
  volume={23 4},
  pages={385-91}
}
An artificial molecule was synthesized by covalently linking the oligosaccharide haptens derived frm Streptococcus pneumoniae type 6A and Neisseria meningitidis group C capsular polysaccharides to the non-toxic mutant protein CRM197, serologically related to diphtheria toxin. Immunochemical analysis using polyclonal and monoclonal antibodies showed in the… CONTINUE READING