A molecular expression signature distinguishing follicular lesions in thyroid carcinoma using preamplification RT-PCR in archival samples

@article{Denning2007AME,
  title={A molecular expression signature distinguishing follicular lesions in thyroid carcinoma using preamplification RT-PCR in archival samples},
  author={Karen M Denning and Paul C. Smyth and Susanne F Cahill and Stephen Finn and Eilish Conlon and Jing Li and Richard John Flavin and Sin{\'e}ad T. Aherne and Simone M. Guenther and Astrid Ferlinz and John J O'leary and Orla M. Sheils},
  journal={Modern Pathology},
  year={2007},
  volume={20},
  pages={1095-1102}
}
Follicular variant of papillary thyroid carcinoma is a lesion that frequently causes difficulties from a diagnostic perspective in the laboratory. The purpose of this study was to interrogate a cohort of archival thyroid lesions using gene expression analysis of a panel of markers proposed to have utility as adjunctive markers in the diagnosis of thyroid neoplasia and follicular variant of papillary thyroid carcinoma in particular. Laser Capture Microdissection was used to procure pure cell… CONTINUE READING