A molecular beacon approach to detecting RAD52 expression in response to DNA damage in human cells.

@article{Riches2010AMB,
  title={A molecular beacon approach to detecting RAD52 expression in response to DNA damage in human cells.},
  author={Lucy C Riches and Anthony M. Lynch and Nigel J. Gooderham},
  journal={Toxicology in vitro : an international journal published in association with BIBRA},
  year={2010},
  volume={24 2},
  pages={652-60}
}
Although DNA damage proteins are infrequently regulated at the transcriptional level, RAD52 mRNA levels appear to be significantly induced in human cells following methyl methanesulphonate (MMS) and Etoposide treatment. Studies have so far been limited to biochemical analysis of cellular extracts and we aimed to extend this observation to whole cells. To… CONTINUE READING