A molecular atlas of cell types and zonation in the brain vasculature

@article{Vanlandewijck2018AMA,
  title={A molecular atlas of cell types and zonation in the brain vasculature},
  author={Michael Vanlandewijck and Liqun He and Maarja Andaloussi M{\"a}e and Johanna Andrae and Koji Ando and Francesca Del Gaudio and Khayrun Nahar and Thibaud Lebouvier and Barbara Lavina and Leonor Gouveia and Ying Sun and Elisabeth Raschperger and Markus R{\"a}s{\"a}nen and Yvette Zarb and Naoki Mochizuki and Annika Keller and Urban Lendahl and Christer Betsholtz},
  journal={Nature},
  year={2018},
  volume={554},
  pages={475-480}
}
Cerebrovascular disease is the third most common cause of death in developed countries, but our understanding of the cells that compose the cerebral vasculature is limited. Here, using vascular single-cell transcriptomics, we provide molecular definitions for the principal types of blood vascular and vessel-associated cells in the adult mouse brain. We uncover the transcriptional basis of the gradual phenotypic change (zonation) along the arteriovenous axis and reveal unexpected cell type… 

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