A molecular atlas of cell types and zonation in the brain vasculature

@article{Vanlandewijck2018AMA,
  title={A molecular atlas of cell types and zonation in the brain vasculature},
  author={M. Vanlandewijck and Liqun He and M. M{\"a}e and J. Andrae and Koji Ando and F. Gaudio and K. Nahar and T. Lebouvier and B. Lavina and Leonor Gouveia and Ying Sun and E. Raschperger and M. R{\"a}s{\"a}nen and Yvette Zarb and N. Mochizuki and A. Keller and U. Lendahl and C. Betsholtz},
  journal={Nature},
  year={2018},
  volume={554},
  pages={475-480}
}
Cerebrovascular disease is the third most common cause of death in developed countries, but our understanding of the cells that compose the cerebral vasculature is limited. Here, using vascular single-cell transcriptomics, we provide molecular definitions for the principal types of blood vascular and vessel-associated cells in the adult mouse brain. We uncover the transcriptional basis of the gradual phenotypic change (zonation) along the arteriovenous axis and reveal unexpected cell type… Expand
The Expanding Cell Diversity of the Brain Vasculature
Zonation-dependent single-endothelial cell transcriptomic changes in the aged brain
Cells of the adult human heart
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 65 REFERENCES
Analysis of the brain mural cell transcriptome
Astrocyte–endothelial interactions at the blood–brain barrier
Pericytes regulate the blood–brain barrier
...
1
2
3
4
5
...