A molecular analysis of the isolated rat posterior frontal and sagittal sutures: differences in gene expression.

@article{Spector2000AMA,
  title={A molecular analysis of the isolated rat posterior frontal and sagittal sutures: differences in gene expression.},
  author={Jason A. Spector and Babak J. Mehrara and Joshua A. Greenwald and Pierre B. Saadeh and Douglas S. Steinbrech and Lotsee Patterson Smith and Michael Thornton Longaker},
  journal={Plastic and reconstructive surgery},
  year={2000},
  volume={106 4},
  pages={
          852-61; discussion 862-7
        }
}
Although it is one of the most commonly occurring craniofacial congenital disabilities, craniosynostosis (the premature fusion of cranial sutures) is nearly impossible to prevent because the molecular mechanisms that regulate the process of cranial suture fusion remain largely unknown. Recent studies have implicated the dura mater in determining the fate of the overlying cranial suture; however, the molecular biology within the suture itself has not been sufficiently investigated. In the murine… CONTINUE READING