A modulating role of prostaglandins in catecholamine release by perfused dog adrenal glands.

Abstract

PGE2, PGE1, PGF2 alpha and PGD2 dose dependently potentiated the ACh-evoked catecholamine (CA) release from perfused dog adrenal glands. These prostaglandins by themselves slightly stimulated CA release. PGE2 potentiated the CA release induced by stimulation of nicotinic or muscarinic cholinergic receptors and also by stimulation with excess K+ or caffeine… (More)

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