A modified damped Richardson-Lucy algorithm to reduce isotropic background effects in spherical deconvolution

Abstract

Spherical deconvolution methods have been applied to diffusion MRI to improve diffusion tensor tractography results in brain regions with multiple fibre crossing. Recent developments, such as the introduction of non-negative constraints on the solution, allow a more accurate estimation of fibre orientations by reducing instability effects due to noise… (More)
DOI: 10.1016/j.neuroimage.2009.09.033

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