A moderate interaction of maltosyl-alpha-cyclodextrin with Caco-2 cells in comparison with the parent cyclodextrin.

@article{Ono2001AMI,
  title={A moderate interaction of maltosyl-alpha-cyclodextrin with Caco-2 cells in comparison with the parent cyclodextrin.},
  author={N. Ono and Hidetoshi Arima and F. Hirayama and K. Uekama},
  journal={Biological & pharmaceutical bulletin},
  year={2001},
  volume={24 4},
  pages={
          395-402
        }
}
  • N. Ono, Hidetoshi Arima, +1 author K. Uekama
  • Published 2001
  • Medicine, Chemistry
  • Biological & pharmaceutical bulletin
  • The cytotoxicity of maltosyl-alpha-cyclodextrin (G2-alpha-CyD) and maltosyl-beta-cyclodextrin (G2-beta-CyD) toward Caco-2 cells was compared with that of natural alpha-cyclodextrin (alpha-CyD), beta-cyclodextrin (beta-CyD) and gamma-cyclodextrin (gamma-CyD). The degree of increase in cytotoxicity was dependent on the CyD's type and the concentration: the cytotoxicity of CyDs at the same concentration increased in the order of gamma-CyD<G2-beta-CyD<G2-alpha-CyD<<alpha-CyD, although beta-CyD… CONTINUE READING
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