A model to predict the permeation kinetics of dimethyl sulfoxide in articular cartilage.

@article{Yu2013AMT,
  title={A model to predict the permeation kinetics of dimethyl sulfoxide in articular cartilage.},
  author={Xiaoyi Yu and Guangming Chen and Shaozhi Zhang},
  journal={Biopreservation and biobanking},
  year={2013},
  volume={11 1},
  pages={
          51-6
        }
}
Cryopreservation of articular cartilage (AC) has excited great interest due to the practical surgical importance of this tissue. Characterization of permeation kinetics of cryoprotective agents (CPA) in AC is important for designing optimal CPA addition/removal protocols to achieve successful cryopreservation. Permeation is predominantly a mass diffusion process. Since the diffusivity is a function of temperature and concentration, analysis of the permeation problem would be greatly facilitated… CONTINUE READING
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A novel method to measure cryoprotectant permeation into intact articular cartilage

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