A model to determine the effect of collagen fiber alignment on heart function post myocardial infarction

Abstract

Adverse remodeling of the left ventricle (LV) following myocardial infarction (MI) leads to heart failure. Recent studies have shown that scar anisotropy is a determinant of cardiac function post-MI, however it remains unclear how changes in extracellular matrix (ECM) organization and structure contribute to changes in LV function. The objective of this… (More)
DOI: 10.1186/1742-4682-11-6

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