A model of the single atrial cell: relation between calcium current and calcium release.

@article{Earm1990AMO,
  title={A model of the single atrial cell: relation between calcium current and calcium release.},
  author={Yung E. Earm and Denis Noble},
  journal={Proceedings of the Royal Society of London. Series B, Biological sciences},
  year={1990},
  volume={240 1297},
  pages={83-96}
}
The hypothesis that calcium release from the sarcoplasmic reticulum in cardiac muscle is induced by rises in free cytosolic calcium (Fabiato 1983, Am. J. Physiol 245) allows the possibility that the release could be at least partly regenerative. There would then be a non-linear relation between calcium current and calcium release. We have investigated this possibility in a single-cell version of the rabbit-atrial model developed by Hilgemann & Noble (1987, Proc. R. Soc. Lond. B 230). The model… CONTINUE READING

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