A model of the evolution of the unusual sex chromosome system of Microtus oregoni

  title={A model of the evolution of the unusual sex chromosome system of Microtus oregoni},
  author={B. Charlesworth and N. Dempsey},
  • B. Charlesworth, N. Dempsey
  • Published 2001
  • Biology, Medicine
  • Heredity
  • In the creeping vole, Microtus oregoni, females are X0 and males are XY. In the female germ line, mitotic nondisjunction ensures that the products of meiosis all carry the X chromosome. Similarly, mitotic nondisjunction in the male germ line leads to the production of 0 and Y sperm. We propose that the present situation in M. oregoni has evolved by invasion of a normal XX/XY system by a mutant X chromosome, X′, with a complete transmission advantage in X′X females, and a complete transmission… CONTINUE READING
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