A model of the Parkinsonian visual system: support for the dark adaptation hypothesis

  title={A model of the Parkinsonian visual system: support for the dark adaptation hypothesis},
  author={Brian Wink and John P. Harris},
  journal={Vision Research},
Considerable evidence suggests that some visual abnormalities in Parkinson's disease are mediated by disruption of dopaminergic processes in the retina. Since dopamine is thought to be involved in the process of dark adaptation, and some of these abnormalities are similar to the changes which accompany dark adaptation in normal subjects, it has been proposed that the parkinsonian retina behaves as though inappropriately dark-adapted. In Parkinson's disease, the apparent contrast of peripherally… CONTINUE READING


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Altered spatio-temporal contrast vision in Parkinson’s disease and MPTP-treated monkeys: the role of dopamine

  • I. Bodis-Wollner
  • I. Bodis-Wollner, & M. Piccolino, Dopaminergic…
  • 1988
Highly Influential
11 Excerpts

The pupillary light reflex in mild Parkinson’s disease

  • S. M. Beaumont, J. P. Harris, J. A. Leendertz, O. T. Phillipson
  • Clinical Vision Sciences,
  • 1987
Highly Influential
9 Excerpts

Vision in Parkinson ’ s disease : what are the deficits and what are their origins ?

  • J. P. Harris, J. E. Calvert, O. T. Phillipson
  • Neuro - ophthalmology
  • 1998
3 Excerpts

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