A model of cardiac contraction based on novel measurements of tension development in human cardiomyocytes.

@article{Land2017AMO,
  title={A model of cardiac contraction based on novel measurements of tension development in human cardiomyocytes.},
  author={Sander Land and So-Jin Park-Holohan and Nicolas Peter Smith and Cristobal G Dos Remedios and Jonathan C Kentish and Steven A Niederer},
  journal={Journal of molecular and cellular cardiology},
  year={2017},
  volume={106},
  pages={
          68-83
        }
}
Experimental data from human cardiac myocytes at body temperature is crucial for a quantitative understanding of clinically relevant cardiac function and development of whole-organ computational models. However, such experimental data is currently very limited. Specifically, important measurements to characterize changes in tension development in human cardiomyocytes that occur with perturbations in cell length are not available. To address this deficiency, in this study we present an… CONTINUE READING
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