A model of brain abscess: septic homologous blood clot emboli in rats.

@article{Matsuura1986AMO,
  title={A model of brain abscess: septic homologous blood clot emboli in rats.},
  author={Hiroyuki Matsuura and Motoshige Kudo and Yusuke Ikeda and Kazuo Isayama and Susumu Nakazawa},
  journal={Journal of neurosurgery},
  year={1986},
  volume={64 1},
  pages={
          125-7
        }
}
Brain abscesses in rats were produced by intra-arterial injection of septic homologous blood clot emboli. The production rate was 100% and the histopathological features closely resembled those seen in other animal models and in spontaneously occurring brain abscesses in humans. This small-animal model may be useful for systematic study of the development of brain abscesses as well as for evaluation of various therapeutic procedures.