A model of 3D-structure of H+, K+-ATPase catalytic subunit derived by homology modeling.

@article{Yan2004AMO,
  title={A model of 3D-structure of H+, K+-ATPase catalytic subunit derived by homology modeling.},
  author={Dong Yan and Yuan-dong Hu and Song Li and Mao-Sheng Cheng},
  journal={Acta pharmacologica Sinica},
  year={2004},
  volume={25 4},
  pages={474-9}
}
AIM To build a model of 3D-structure of H(+), K(+)-ATPase catalytic subunit for theoretical study and anti-ulcer drug design. METHODS The model was built on the basis of structural data from the Ca(2+)-ATPase. Structurally conserved regions were defined by amino acid sequence comparisons, optimum interconnecting loops were selected from the protein databank, and amino (N)- and carboxyl (C)-terminal ends were generated as random coil structures. Applying molecular mechanics method then… CONTINUE READING
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Membrane topology and omeprazole labeling of the gastric H + , K + - ATPase

  • M Besancon, JM Shin, F Mercier, K Munson, M Miller, S Hersey
  • Biochemistry
  • 1993

Na, K-ATPase complexes in Xenopus oocytes

  • M Besancon, A Simon, G Sachs, JM. Shin
  • J Biol Chem
  • 1992

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