A model for the 3D chromatin architecture of pro and eukaryotes.

@article{Heermann2012AMF,
  title={A model for the 3D chromatin architecture of pro and eukaryotes.},
  author={Dieter W. Heermann and Hansjoerg Jerabek and Lei Liu and Yixue Li},
  journal={Methods},
  year={2012},
  volume={58 3},
  pages={307-14}
}
How do chromosomes fold and how does this depend on the organism and type of cell? This question has been addressed by a model and a methodology that uses only very basic constituents to capture the relevant features of folding. Key is the dynamic formation of loops within the chromosome. With this and entropy we show that the model is capable to describe… CONTINUE READING