A model for sequestration of the transmission stages of Plasmodium falciparum: adhesion of gametocyte-infected erythrocytes to human bone marrow cells.

@article{Rogers2000AMF,
  title={A model for sequestration of the transmission stages of Plasmodium falciparum: adhesion of gametocyte-infected erythrocytes to human bone marrow cells.},
  author={Nicola J Rogers and Belinda S. Hall and Jacktone Obiero and Geoffrey A T Targett and Colin J. Sutherland},
  journal={Infection and immunity},
  year={2000},
  volume={68 6},
  pages={3455-62}
}
With the aim of developing an appropriate in vitro model of the sequestration of developing Plasmodium falciparum sexual-stage parasites, we have investigated the cytoadherence of gametocytes to human bone marrow cells of stromal and endothelial origin. Developing stage III and IV gametocytes, but not mature stage V gametocytes, adhere to bone marrow cells in significantly higher densities than do asexual-stage parasites, although these adhesion densities are severalfold lower than those… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 31 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 30 references

Characterisation of the response of human bone marrow endothelial cells to in vitro irradiation

  • Gaugler, M.-H, +5 authors A. van der Meeren
  • Br. J. Haematol
  • 1998

Similar Papers

Loading similar papers…