A model for red blood cell motion in glycocalyx-lined capillaries.

@article{Secomb1998AMF,
  title={A model for red blood cell motion in glycocalyx-lined capillaries.},
  author={Timothy W. Secomb and Richard Hsu and Axel Radlach Pries},
  journal={The American journal of physiology},
  year={1998},
  volume={274 3 Pt 2},
  pages={H1016-22}
}
The interior surfaces of capillaries are lined with a layer (glycocalyx) of macromolecules bound or absorbed to the endothelium. Here, a theoretical model is used to analyze the effects of the glycocalyx on hematocrit and resistance to blood flow in capillaries. The glycocalyx is represented as a porous layer that resists penetration by red blood cells. Axisymmetric red blood cell shapes are assumed, and effects of cell membrane shear elasticity are included. Lubrication theory is used to… CONTINUE READING