Naturally acquired antibodies to merozoite surface protein (MSP)-1(19) and cumulative exposure to Plasmodium falciparum and Plasmodium vivax in remote populations of the Amazon Basin of Brazil.
A model is developed to estimate the duration for which malaria antibody levels in the blood remain high in a closed population. This estimate can be used to calculate the transmission rate within a region, in conjunction with the serological information contained in the population. The model is used on data obtained from a study of malaria in the Philippines and shows excellent agreement. It is subsequently utilised for predictions and seems to be an appropriate vehicle for this purpose.