A model for local accumulation of bone imaging radiopharmaceuticals.

  title={A model for local accumulation of bone imaging radiopharmaceuticals.},
  author={Michael A. King and Robert W. Kilpper and David A. Weber},
  journal={Journal of nuclear medicine : official publication, Society of Nuclear Medicine},
  volume={18 11},
A simple models, having phenomenological parameters as variables, is developed for predicting local radioactive tracer accumulation in bone. Blood delivering tracer to one gram of bone is treated as a compartment separate from the remainder of the circulation in order to observe the effects produced by variations in both bone flow and barrier permeability… CONTINUE READING