A model for ligand binding to hexacoordinate hemoglobins.

  title={A model for ligand binding to hexacoordinate hemoglobins.},
  author={James T. Trent and Angela N. Hvitved and Mark S Hargrove},
  volume={40 20},
Hexacoordinate hemoglobins are heme proteins capable of reversible intramolecular coordination of the ligand binding site by an amino acid side chain from within the heme pocket. Examples of these proteins are found in many living organisms ranging from prokaryotes to humans. The nonsymbiotic hemoglobins (nsHbs) are a class of hexacoordinate heme proteins present in all plants. The nsHb from rice (rHb1) has been used as a model system to develop methods for determining rate constants… CONTINUE READING